BRAP 抗体 (AA 560-592)
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- 抗原 See all BRAP 抗体
- BRAP (BRCA1 Associated Protein (BRAP))
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抗原表位
- AA 560-592
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-BRAP Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 560 and 592
- 亚型
- IgG
- Top Product
- Discover our top product BRAP Primary Antibody
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- 应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- BRAP (BRCA1 Associated Protein (BRAP))
- 别名
- BRAP (BRAP 产品)
- 别名
- imp antibody, MGC68778 antibody, zgc:92894 antibody, BRAP antibody, BRAP2 antibody, IMP antibody, RNF52 antibody, 3010002G07Rik antibody, BRCA1 associated protein S homeolog antibody, BRCA1 associated protein antibody, BRCA1-associated protein antibody, brca1-associated protein antibody, brap.S antibody, brap antibody, BRAP antibody, NAEGRDRAFT_81654 antibody, CC1G_00971 antibody, CpipJ_CPIJ003557 antibody, Tsp_05101 antibody, LOC100282389 antibody, Brap antibody
- 背景
- Background: BRCA1-associated protein (BRAP) negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. BRAP acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. BRAP may also act as a cytoplasmic retention protein with a role in regulating nuclear transport [taken from the Universal Protein Resource (UniProt) Q7Z569].
- 基因ID
- 8315
- NCBI登录号
- NP_006759
- UniProt
- Q7Z569
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