SPAG5 抗体 (AA 875-925)
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- 抗原 See all SPAG5 抗体
- SPAG5 (Sperm Associated Antigen 5 (SPAG5))
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抗原表位
- AA 875-925
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPAG5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-Astrin/MAP126 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 875 and 925
- 亚型
- IgG
- Top Product
- Discover our top product SPAG5 Primary Antibody
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- 应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- SPAG5 (Sperm Associated Antigen 5 (SPAG5))
- 别名
- Astrin/MAP126 (SPAG5 产品)
- 别名
- SPAG5 antibody, DEEPEST antibody, MAP126 antibody, hMAP126 antibody, AI874642 antibody, D11Bhm180e antibody, Deepest antibody, Mastrin antibody, S17 antibody, sperm associated antigen 5 antibody, sperm-associated antigen 5 antibody, SPAG5 antibody, LOC739263 antibody, Spag5 antibody
- 背景
- Background: Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta).
- 基因ID
- 10615
- NCBI登录号
- NP_006452
- UniProt
- Q96R06
- 途径
- M Phase
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