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SPAG5 抗体 (AA 875-925)

SPAG5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7451646
发货至: 中国
  • 抗原 See all SPAG5 抗体
    SPAG5 (Sperm Associated Antigen 5 (SPAG5))
    抗原表位
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 875-925
    适用
    • 17
    • 2
    • 1
    • 1
    • 1
    宿主
    • 17
    • 1
    克隆类型
    • 17
    • 1
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPAG5 antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-Astrin/MAP126 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 875 and 925
    亚型
    IgG
    Top Product
    Discover our top product SPAG5 Primary Antibody
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    SPAG5 (Sperm Associated Antigen 5 (SPAG5))
    别名
    Astrin/MAP126 (SPAG5 产品)
    别名
    SPAG5 antibody, DEEPEST antibody, MAP126 antibody, hMAP126 antibody, AI874642 antibody, D11Bhm180e antibody, Deepest antibody, Mastrin antibody, S17 antibody, sperm associated antigen 5 antibody, sperm-associated antigen 5 antibody, SPAG5 antibody, LOC739263 antibody, Spag5 antibody
    背景
    Background: Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta).
    基因ID
    10615
    NCBI登录号
    NP_006452
    UniProt
    Q96R06
    途径
    M Phase
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