RRP8 抗体 (AA 406-456)
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- 抗原 See all RRP8 抗体
- RRP8 (Ribosomal RNA Processing 8 (RRP8))
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抗原表位
- AA 406-456
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RRP8 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP)
- 原理
- Rabbit anti-RRP8 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 406 and 456
- 亚型
- IgG
- Top Product
- Discover our top product RRP8 Primary Antibody
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anti-Ribosomal RNA Processing 8 (RRP8) antibody
RRP8 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (Internal Region) antibodyRRP8 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 1-456) antibodyRRP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 271-320) antibodyRRP8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 100-149) antibodyRRP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 89-138) antibodyRRP8 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (N-Term) antibodyRRP8 适用: 人, 大鼠, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-RRP8 antibody ABIN7453202.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- RRP8 (Ribosomal RNA Processing 8 (RRP8))
- 别名
- RRP8 (RRP8 产品)
- 别名
- KIAA0409 antibody, 1500003O22Rik antibody, 2900001K19Rik antibody, AW538116 antibody, RGD1308302 antibody, ribosomal RNA processing 8 antibody, ribosomal RNA processing 8, methyltransferase, homolog (yeast) antibody, RRP8 antibody, Rrp8 antibody
- 背景
- Background: Ribosomal RNA-processing protein (RRP8) is an essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown [taken from the Universal Protein Resource (UniProt) O43159].
- 基因ID
- 23378
- NCBI登录号
- NP_056139
- UniProt
- O43159
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