电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MAML2 抗体 (AA 250-300)

MAML2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7451271
发货至: 中国
  • 抗原 See all MAML2 抗体
    MAML2 (Mastermind-Like 2 (MAML2))
    抗原表位
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-300
    适用
    • 26
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 16
    • 11
    克隆类型
    • 16
    • 11
    多克隆
    标记
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAML2 antibody is un-conjugated
    应用范围
    • 23
    • 12
    • 11
    • 9
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunoprecipitation (IP)
    原理
    Rabbit anti-MAML2 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 250 and 300
    亚型
    IgG
    Top Product
    Discover our top product MAML2 Primary Antibody
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended. Use rabbit anti-MAML2 antibody A300-682A.

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    MAML2 (Mastermind-Like 2 (MAML2))
    别名
    MAML2 (MAML2 产品)
    别名
    5930431H10 antibody, BC032967 antibody, MAM-3 antibody, MAM2 antibody, MAM3 antibody, MLL-MAML2 antibody, mastermind like 2 (Drosophila) antibody, mastermind-like transcriptional coactivator 2 antibody, mastermind like transcriptional coactivator 2 antibody, Maml2 antibody, MAML2 antibody
    背景
    Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML2 is a critical coactivator for NOTCH signaling. MAML2 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML2 has been identified in a chromosomal rearrangement and fusion with MECT1 in mucoepidermoid carcinomas, secondary acute myeloid leukemia, hidradenomas, and myelodysplastic syndrome. MECT1 is a CREB regulator, and when fused with the transactivational domain of MAML2, imparts constitutive activation of CREB-dependent transcription that may promote oncogenesis.
    基因ID
    84441
    UniProt
    Q8IZL2
You are here:
客服