Importin 11 抗体 (AA 825-875)
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- 抗原 See all Importin 11 (IPO11) 抗体
- Importin 11 (IPO11)
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抗原表位
- AA 825-875
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Importin 11 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP)
- 原理
- Rabbit anti-Importin 11/IPO11 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 825 and 875
- 亚型
- IgG
- Top Product
- Discover our top product IPO11 Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-Importin 11/IPO11 antibody ABIN7450360.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- Importin 11 (IPO11)
- 别名
- Importin 11/IPO11 (IPO11 产品)
- 别名
- MGC83107 antibody, IPO11 antibody, slrn antibody, ranbp11 antibody, RanBP11 antibody, 1700081H05Rik antibody, 2510001A17Rik antibody, AI314624 antibody, AW555235 antibody, E330021B14Rik antibody, Ranbp11 antibody, importin 11 S homeolog antibody, importin 11 antibody, importin-11 antibody, ipo11.S antibody, ipo11 antibody, IPO11 antibody, AFUA_1G03590 antibody, BDBG_04626 antibody, LOC100162908 antibody, Ipo11 antibody
- 背景
- Background: Importin 11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates, and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Importin 11/IPO11 mediates the nuclear import of UBE2E3, and of RPL12 (By similarity) [taken from the Universal Protein Resource (UniProt) Q9UI26].
- 基因ID
- 51194
- UniProt
- Q9UI26
- 途径
- Protein targeting to Nucleus
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