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IMPA1 抗体 (AA 25-75)

IMPA1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7451266
发货至: 中国
  • 抗原 See all IMPA1 抗体
    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
    抗原表位
    • 10
    • 1
    • 1
    • 1
    AA 25-75
    适用
    • 32
    • 14
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 29
    • 3
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This IMPA1 antibody is un-conjugated
    应用范围
    • 13
    • 7
    • 7
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunoprecipitation (IP)
    原理
    Rabbit anti-IMPA1 Antibody, Affinity Purified
    预测反应
    Orangutan
    纯化方法
    Affinity Purified
    免疫原
    Between AA 25 and 75
    亚型
    IgG
    Top Product
    Discover our top product IMPA1 Primary Antibody
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended. Use rabbit anti-IMPA1 antibody ABIN7450359.

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
    别名
    IMPA1 (IMPA1 产品)
    别名
    zgc:100926 antibody, 2610002K09Rik antibody, 2900059K10Rik antibody, AI325909 antibody, IMP antibody, IMPA antibody, impa antibody, inositol monophosphatase 1 antibody, inositol(myo)-1(or 4)-monophosphatase 1 antibody, inositol (myo)-1(or 4)-monophosphatase 1 antibody, inositol monophosphatase antibody, inositol(myo)-1(or 4)-monophosphatase 1 S homeolog antibody, impa1 antibody, Impa1 antibody, IMPA1 antibody, impa1.S antibody
    背景
    Background: Inositol monophosphatase 1 (IMPA1) is an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorde [taken from NCBI Entrez Gene (Gene ID: 3612)].
    基因ID
    3612
    UniProt
    P29218
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