MYO5B 抗体 (AA 50-100)
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- 抗原 See all MYO5B products
- MYO5B (Myosin VB (MYO5B))
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抗原表位
- AA 50-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYO5B antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP)
- 原理
- Rabbit anti-MYO5B Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 50 and 100
- 亚型
- IgG
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451161 has not performed satisfactorily when used for WB of MYO5B in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MYO5B.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- MYO5B (Myosin VB (MYO5B))
- 别名
- MYO5B (MYO5B 产品)
- 别名
- AI661750 antibody, mKIAA1119 antibody, Myr6 antibody, myosin VB antibody, myosin Vb antibody, MYO5B antibody, Myo5b antibody
- 背景
- Background: Myosin 5B may be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. MYO5B is required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Also, together with RAB11A, MYO5B participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A it participates in epithelial cell polarization. Together with RAB25 MYO5B regulates transcytosis [taken from the Universal Protein Resource (UniProt) Q9ULV0].
- 基因ID
- 4645
- UniProt
- Q9ULV0
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