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MYO5B 抗体 (AA 50-100)

适用: 人 IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7451161
发货至: 中国
  • 抗原 See all MYO5B products
    MYO5B (Myosin VB (MYO5B))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    AA 50-100
    适用
    • 11
    • 7
    • 1
    宿主
    • 11
    克隆类型
    • 11
    多克隆
    标记
    • 11
    This MYO5B antibody is un-conjugated
    应用范围
    • 10
    • 7
    • 4
    • 4
    • 1
    • 1
    Immunoprecipitation (IP)
    原理
    Rabbit anti-MYO5B Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    Between AA 50 and 100
    亚型
    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended. ABIN7451161 has not performed satisfactorily when used for WB of MYO5B in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MYO5B.

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    MYO5B (Myosin VB (MYO5B))
    别名
    MYO5B (MYO5B 产品)
    别名
    AI661750 antibody, mKIAA1119 antibody, Myr6 antibody, myosin VB antibody, myosin Vb antibody, MYO5B antibody, Myo5b antibody
    背景
    Background: Myosin 5B may be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. MYO5B is required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Also, together with RAB11A, MYO5B participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A it participates in epithelial cell polarization. Together with RAB25 MYO5B regulates transcytosis [taken from the Universal Protein Resource (UniProt) Q9ULV0].
    基因ID
    4645
    UniProt
    Q9ULV0
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