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USP11 抗体 (AA 870-920)

USP11 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7450882
发货至: 中国
  • 抗原 See all USP11 抗体
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    抗原表位
    • 11
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 870-920
    适用
    • 47
    • 13
    • 12
    • 1
    • 1
    宿主
    • 41
    • 6
    • 1
    克隆类型
    • 35
    • 13
    多克隆
    标记
    • 24
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This USP11 antibody is un-conjugated
    应用范围
    • 33
    • 21
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-USP11 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    Between AA 870 and 920
    亚型
    IgG
    Top Product
    Discover our top product USP11 Primary Antibody
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    别名
    USP11 (USP11 产品)
    别名
    USP11 antibody, DKFZp459L098 antibody, UHX1 antibody, 6230415D12Rik antibody, mKIAA4085 antibody, Uhx1 antibody, ubiquitin specific peptidase 11 antibody, universal stress protein antibody, USP11 antibody, RR_RS19935 antibody, Usp11 antibody
    背景
    Background: Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 11 (USP11) is a member of this family. USP11 has been found to associate with several proteins and may have functions independent of its deubiquitinating activity. USP11 deubiquitinates and associates with the RanGTP-binding protein, RanBPM. It has also been found to associate with BRCA2 and participate in the BRCA2 DNA damage related pathway, however, it does not appear to be involved in BRCA2 deubiquitination. USP11 also appears to play a role in the regulation of the IKKalpha and p53 signaling pathway by a mechanism independent of it deubiquitination activity.
    基因ID
    8237
    UniProt
    P51784
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