USP11 抗体 (AA 870-920)
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- 抗原 See all USP11 抗体
- USP11 (Ubiquitin Specific Peptidase 11 (USP11))
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抗原表位
- AA 870-920
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-USP11 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 870 and 920
- 亚型
- IgG
- Top Product
- Discover our top product USP11 Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- USP11 (Ubiquitin Specific Peptidase 11 (USP11))
- 别名
- USP11 (USP11 产品)
- 别名
- USP11 antibody, DKFZp459L098 antibody, UHX1 antibody, 6230415D12Rik antibody, mKIAA4085 antibody, Uhx1 antibody, ubiquitin specific peptidase 11 antibody, universal stress protein antibody, USP11 antibody, RR_RS19935 antibody, Usp11 antibody
- 背景
- Background: Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 11 (USP11) is a member of this family. USP11 has been found to associate with several proteins and may have functions independent of its deubiquitinating activity. USP11 deubiquitinates and associates with the RanGTP-binding protein, RanBPM. It has also been found to associate with BRCA2 and participate in the BRCA2 DNA damage related pathway, however, it does not appear to be involved in BRCA2 deubiquitination. USP11 also appears to play a role in the regulation of the IKKalpha and p53 signaling pathway by a mechanism independent of it deubiquitination activity.
- 基因ID
- 8237
- UniProt
- P51784
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