UPF3B 抗体 (AA 300-350)
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- 抗原 See all UPF3B 抗体
- UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
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抗原表位
- AA 300-350
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UPF3B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-UPF3B Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 300 and 350
- 亚型
- IgG
- Top Product
- Discover our top product UPF3B Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
- 别名
- UPF3B (UPF3B 产品)
- 别名
- HUPF3B antibody, MRXS14 antibody, RENT3B antibody, UPF3X antibody, 5730594O13Rik antibody, AI317193 antibody, AW541158 antibody, RGD1560264 antibody, UPF3B, regulator of nonsense mediated mRNA decay antibody, UPF3 regulator of nonsense transcripts homolog B (yeast) antibody, UPF3B antibody, Upf3b antibody
- 背景
- Background: UPF3B (UPF regulator of nonsense transcripts homolog B) is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. UPF3B recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2, UPF3B stimulates both ATPase and RNA helicase activities of UPF1 [taken from the Universal Protein Resource (UniProt) Q9BZI7].
- 基因ID
- 65109
- NCBI登录号
- NP_542199
- UniProt
- Q9BZI7
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