SPG20 抗体 (AA 350-400)
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- 抗原 See all SPG20 抗体
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
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抗原表位
- AA 350-400
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPG20 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-SPG20 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 350 and 400
- 亚型
- IgG
- Top Product
- Discover our top product SPG20 Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
- 别名
- SPG20 (SPG20 产品)
- 别名
- SPARTIN antibody, TAHCCP1 antibody, AI840044 antibody, C79168 antibody, mKIAA0610 antibody, spartin antibody, Spg20 antibody, spg20a antibody, zgc:172059 antibody, spg20b antibody, zgc:153766 antibody, spartin antibody, spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) antibody, spartin a antibody, spartin b antibody, SPART antibody, Spg20 antibody, Spart antibody, sparta antibody, spartb antibody
- 背景
- Background: Spastic paraplegia 20 protein (SPG20) is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Mutations associated with the SPG20 gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome) [taken from NCBI Entrez Gene (Gene ID: 23111)].
- 基因ID
- 23111
- UniProt
- Q8N0X7
- 途径
- Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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