SH3BP2 抗体 (AA 150-200)
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- 抗原 See all SH3BP2 抗体
- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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抗原表位
- AA 150-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SH3BP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-SH3BP2 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 150 and 200
- 亚型
- IgG
- Top Product
- Discover our top product SH3BP2 Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
- 别名
- SH3BP2 (SH3BP2 产品)
- 别名
- SH3BP2 antibody, 3BP-2 antibody, 3BP2 antibody, CRBM antibody, CRPM antibody, SH3 domain binding protein 2 antibody, SH3-domain binding protein 2 antibody, SH3BP2 antibody, Sh3bp2 antibody
- 背景
- Background: SH3 domain-binding protein 2 (SH3BP2) N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism, an autosomal dominant inherited syndrome characterized by excessive bone degradation of the upper and lower jaws followed by development of fibrous tissue masses and characteristic facial swelling [taken from NCBI Entrez Gene (Gene ID: 6452)].
- 基因ID
- 6452
- NCBI登录号
- NP_001116153
- UniProt
- P78314
- 途径
- TCR Signaling
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