MPRIP 抗体 (AA 400-450)
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- 抗原 See all MPRIP 抗体
- MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
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抗原表位
- AA 400-450
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MPRIP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-RIP3 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 400 and 450
- 亚型
- IgG
- Top Product
- Discover our top product MPRIP Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
- 别名
- RIP3 (MPRIP 产品)
- 别名
- M-RIP antibody, MRIP antibody, RHOIP3 antibody, RIP3 antibody, p116Rip antibody, 9530046C02 antibody, AA536749 antibody, AI647711 antibody, C76423 antibody, Rhoip3 antibody, mKIAA0864 antibody, M-rip antibody, Mrip antibody, myosin phosphatase Rho interacting protein antibody, MPRIP antibody, Mprip antibody
- 背景
- Background: Receptor-interacting serine/threonine-protein kinase 3 (RIP3) is essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIP3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIP3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production [taken from the Universal Protein Resource (UniProt) Q9Y572].
- 基因ID
- 11035
- NCBI登录号
- NP_006862
- UniProt
- Q9Y572
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