PAN2 抗体 (AA 1-50)
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- 抗原 See all PAN2 抗体
- PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
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抗原表位
- AA 1-50
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-PAN2/USP52 Antibody, Affinity Purified
- 预测反应
- Rat
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 1 and 50
- 亚型
- IgG
- Top Product
- Discover our top product PAN2 Primary Antibody
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anti-PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2) (AA 628-908) antibody
PAN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2) (AA 1099-1198) antibodyPAN2 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 6A7 unconjugated
anti-PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2) (AA 700-1000) antibodyPAN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
- 别名
- PAN2/USP52 (PAN2 产品)
- 别名
- USP52 antibody, 1200014O24Rik antibody, AI047843 antibody, AW742773 antibody, Usp52 antibody, mKIAA0710 antibody, PAN2 antibody, pan2 antibody, PAN2 poly(A) specific ribonuclease subunit antibody, PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) antibody, PAN2 poly(A) specific ribonuclease subunit S homeolog antibody, PAN2 antibody, Pan2 antibody, pan2.S antibody
- 背景
- Background: PAB-dependent poly(A)-specific ribonuclease subunit PAN2 is the catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1 [taken from the Universal Protein Resource (UniProt) Q504Q3].
- 基因ID
- 9924
- UniProt
- Q504Q3
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