NBR1 抗体 (AA 916-966)
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- 抗原 See all NBR1 抗体
- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
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抗原表位
- AA 916-966
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NBR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-NBR1 Antibody, Affinity Purified
- 预测反应
- Orangutan
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 916 and 966
- 亚型
- IgG
- Top Product
- Discover our top product NBR1 Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
- 别名
- NBR1 (NBR1 产品)
- 别名
- fa99f08 antibody, wu:fa99f08 antibody, MGC69008 antibody, NBR1 antibody, 1A1-3B antibody, M17S2 antibody, mKIAA0049 antibody, Ca125 antibody, RGD1311421 antibody, neighbor of brca1 gene 1a antibody, neighbor of BRCA1 gene 1 L homeolog antibody, NBR1, autophagy cargo receptor antibody, neighbor of Brca1 gene 1 antibody, nbr1a antibody, nbr1.L antibody, NBR1 antibody, Nbr1 antibody
- 背景
- Background: NBR1 (Next to BRCA1 gene 1 protein) was originally identified as an ovarian tumor antigen monitored in ovarian cancer.NBR1 contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. The gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene [taken from NCBI Entrez Gene (Gene ID: 4077)].
- 基因ID
- 4077
- UniProt
- Q14596
- 途径
- Autophagy
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