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NBR1 抗体 (AA 916-966)

NBR1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7450479
发货至: 中国
  • 抗原 See all NBR1 抗体
    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
    抗原表位
    • 3
    • 3
    • 2
    • 1
    • 1
    AA 916-966
    适用
    • 19
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 13
    • 8
    克隆类型
    • 16
    • 5
    多克隆
    标记
    • 21
    This NBR1 antibody is un-conjugated
    应用范围
    • 17
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-NBR1 Antibody, Affinity Purified
    预测反应
    Orangutan
    纯化方法
    Affinity Purified
    免疫原
    Between AA 916 and 966
    亚型
    IgG
    Top Product
    Discover our top product NBR1 Primary Antibody
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
    别名
    NBR1 (NBR1 产品)
    别名
    fa99f08 antibody, wu:fa99f08 antibody, MGC69008 antibody, NBR1 antibody, 1A1-3B antibody, M17S2 antibody, mKIAA0049 antibody, Ca125 antibody, RGD1311421 antibody, neighbor of brca1 gene 1a antibody, neighbor of BRCA1 gene 1 L homeolog antibody, NBR1, autophagy cargo receptor antibody, neighbor of Brca1 gene 1 antibody, nbr1a antibody, nbr1.L antibody, NBR1 antibody, Nbr1 antibody
    背景
    Background: NBR1 (Next to BRCA1 gene 1 protein) was originally identified as an ovarian tumor antigen monitored in ovarian cancer.NBR1 contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. The gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene [taken from NCBI Entrez Gene (Gene ID: 4077)].
    基因ID
    4077
    UniProt
    Q14596
    途径
    Autophagy
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