ZBTB33 抗体 (AA 375-425)
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- 抗原 See all ZBTB33 抗体
- ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))
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抗原表位
- AA 375-425
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZBTB33 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-Kaiso Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 375 and 425
- 亚型
- IgG
- Top Product
- Discover our top product ZBTB33 Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))
- 别名
- Kaiso (ZBTB33 产品)
- 别名
- kaiso antibody, ZNF-kaiso antibody, ZNF348 antibody, AW260253 antibody, E130014G12Rik antibody, Kaiso antibody, Znf-kaiso antibody, RGD1566309 antibody, zinc finger and BTB domain containing 33 S homeolog antibody, zinc finger and BTB domain containing 33 antibody, zbtb33.S antibody, ZBTB33 antibody, Zbtb33 antibody
- 背景
- Background: Transcriptional regulator Kaiso possesses bimodal DNA-binding specificity and binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. Kaiso contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Kaiso may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. [taken from NCBI Entrez Gene (Gene ID: 10009)].
- 基因ID
- 10009
- NCBI登录号
- NP_006768
- UniProt
- Q86T24
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