Desmoplakin 抗体 (AA 1600-1650)
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- 抗原 See all Desmoplakin (DSP) 抗体
- Desmoplakin (DSP)
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抗原表位
- AA 1600-1650
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Desmoplakin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-Desmoplakin Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 1600 and 1650
- 亚型
- IgG
- Top Product
- Discover our top product DSP Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- Desmoplakin (DSP)
- 别名
- Desmoplakin (DSP 产品)
- 别名
- DP antibody, DPI antibody, DPII antibody, DSP antibody, dpi antibody, dpii antibody, 2300002E22Rik antibody, 5730453H04Rik antibody, AA407887 antibody, AA407888 antibody, AW109828 antibody, im:6911953 antibody, sb:cb570 antibody, wu:fc17a08 antibody, wu:fk73d01 antibody, desmoplakin antibody, Desmoplakin antibody, ORF113 antibody, desmoplakin a antibody, ORF112 DESMOPLAKIN antibody, orf102 antibody, orf91; similar to Cydia pomonella granulovirus orf112 antibody, ORF62 antibody, ORF-66 antibody, ORF57 antibody, agip105 antibody, similar to XcORF133; similar to HaGV desmoplakin antibody, desmoplakin L homeolog antibody, ORF96 antibody, DSP antibody, PhopGV104 antibody, ORF-59 desmoplakin antibody, desmop antibody, Dsp antibody, dsp antibody, desmoplakin antibody, dspa antibody, orf112 desmoplakin antibody, ClgVgp102 antibody, COGV_gp091 antibody, APNV_p087 antibody, CBNV_gp066 antibody, EONV_gp057 antibody, OLNV_gp066 antibody, AgipMNPV_gp105 antibody, HaMNV_gp106 antibody, EupsNPV_gp065 antibody, PsunGV_gp139 antibody, dsp.L antibody, ClanGV_gp096 antibody
- 背景
- Background: Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in DSP, the gene encoding desmoplakin, are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus [taken from NCBI Entrez Gene (Gene ID: 1832)].
- 基因ID
- 1832
- NCBI登录号
- NP_004406
- UniProt
- P15924
- 途径
- Cell-Cell Junction Organization
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