MAML1 抗体 (AA 75-125)
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- 抗原 See all MAML1 抗体
- MAML1 (Mastermind-Like 1 (MAML1))
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抗原表位
- AA 75-125
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAML1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-MAML1 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 75 and 125
- 亚型
- IgG
- Top Product
- Discover our top product MAML1 Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- MAML1 (Mastermind-Like 1 (MAML1))
- 别名
- MAML1 (MAML1 产品)
- 别名
- mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
- 背景
- Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes.
- 基因ID
- 9794
- NCBI登录号
- NP_055572
- UniProt
- Q92585
- 途径
- Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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