EPH Receptor A5 抗体 (AA 451-550)
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- 抗原 See all EPH Receptor A5 (EPHA5) 抗体
- EPH Receptor A5 (EPHA5)
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抗原表位
- AA 451-550
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPH Receptor A5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Cow,Pig,Rabbit,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EphA5/Eph receptor A5
- 亚型
- IgG
- Top Product
- Discover our top product EPHA5 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- EPH Receptor A5 (EPHA5)
- 别名
- Eph receptor A5 (EPHA5 产品)
- 别名
- CEK7 antibody, EHK-1 antibody, EHK1 antibody, EK7 antibody, HEK7 antibody, TYRO4 antibody, AI854630 antibody, AW125296 antibody, Cek7 antibody, Ehk1 antibody, Els1 antibody, Hek7 antibody, Rek7 antibody, bsk antibody, Els1. antibody, EPHA5 antibody, EPH receptor A5 antibody, Eph receptor A5 antibody, EPHA5 antibody, epha5 antibody, Epha5 antibody
- 背景
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Synonyms: EK7, CEK7, EHK1, HEK7, EHK-1, TYRO4, Ephrin type-A receptor 5, Brain-specific kinase, EPH homology kinase 1, EPH-like kinase 7, EPHA5, BSK
Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).
- 基因ID
- 2044
- UniProt
- P54756
- 途径
- RTK signaling
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