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Stim2 抗体 (AA 650-700)

Stim2 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7449833
发货至: 中国
  • 抗原 See all Stim2 抗体
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    抗原表位
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 650-700
    适用
    • 37
    • 13
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 35
    • 1
    • 1
    克隆类型
    • 37
    多克隆
    标记
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    This Stim2 antibody is un-conjugated
    应用范围
    • 33
    • 27
    • 19
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-STIM2 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    Between AA 650 and 700
    亚型
    IgG
    Top Product
    Discover our top product Stim2 Primary Antibody
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    别名
    STIM2 (Stim2 产品)
    别名
    STIM2 antibody, stromal interaction molecule 2 antibody, STIM2 antibody, stim2 antibody, Stim2 antibody
    背景
    Background: STIM2 (stromal interaction molecule 2) plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Stim2 functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. It regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, STIM2 translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI. STIM2 may inhibit STIM1-mediated Ca(2+) influx  [taken from the Universal Protein Resource (UniProt) Q9P246].
    基因ID
    57620
    NCBI登录号
    NP_065911
    UniProt
    Q9P246
    途径
    TCR Signaling, BCR Signaling
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