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RENT2/UPF2 抗体 (AA 1-50)

UPF2 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7449802
发货至: 中国
  • 抗原 See all RENT2/UPF2 (UPF2) 抗体
    RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 1-50
    适用
    • 24
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 23
    • 1
    克隆类型
    • 24
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    This RENT2/UPF2 antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 13
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-RENT2 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    Between AA 1 and 50
    亚型
    IgG
    Top Product
    Discover our top product UPF2 Primary Antibody
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
    别名
    RENT2 (UPF2 产品)
    别名
    HUPF2 antibody, RENT2 antibody, smg-3 antibody, UPF2, regulator of nonsense mediated mRNA decay antibody, UPF2 regulator of nonsense transcripts homolog (yeast) antibody, UPF2 antibody, Upf2 antibody, upf2 antibody
    背景
    Background: Regulator of nonsense transcripts 2 (RENT2), also known as UPF2, is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). RENT2 is recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B, RENT2 stimulates both ATPase and RNA helicase activities of UPF1. RENT2 binds spliced mRNA [taken from the Universal Protein Resource (UniProt) Q9HAU5].
    基因ID
    26019
    NCBI登录号
    NP_056357
    UniProt
    Q9HAU5
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