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CD45RO 抗体

CD45RO 适用: 人 WB, IHC, IF (p), ICC, mIF 宿主: 小鼠 Monoclonal UCHL-1 unconjugated
产品编号 ABIN7449553
发货至: 中国
  • 抗原 See all CD45RO products
    CD45RO
    适用
    • 66
    • 12
    • 12
    • 11
    • 11
    宿主
    • 54
    • 12
    小鼠
    克隆类型
    • 54
    • 12
    单克隆
    标记
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    This CD45RO antibody is un-conjugated
    应用范围
    • 52
    • 27
    • 21
    • 13
    • 10
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    • 4
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    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Multiplex Immunofluorescence (mIF)
    原理
    Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]
    免疫原
    Cultured T-cells from an IL-2-dependent T-cell line (CA1)
    克隆位点
    UCHL-1
    亚型
    IgG
  • 应用备注

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 05:10:00

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    CD45RO
    别名
    CD45RO (CD45RO 产品)
    背景
    Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].
    基因ID
    5788
    NCBI登录号
    NP_002829
    UniProt
    P08575
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