Apo-B100 抗体 (Biotin)
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- 抗原 See all Apo-B100 抗体
- Apo-B100 (Apoprotein B100 (Apo-B100))
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Apo-B100 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Goat anti-Human Apo B-100 [B06] Antibody Biotin Conjugated
- 免疫原
- Human Apolipoprotein B100
- 克隆位点
- B06
- 亚型
- IgG
- Top Product
- Discover our top product Apo-B100 Primary Antibody
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- 应用备注
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WB: 1:1,000 - 1:80,000
ELISA: 1:1,000 - 1:80,000
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- Apo-B100 (Apoprotein B100 (Apo-B100))
- 别名
- ApoB-100 (Apo-B100 产品)
- 别名
- Ac1-060 antibody, Apo B-100 antibody, ApoB-100 antibody, ApoB-48 antibody, apolipoprotein B antibody, Apob antibody
- 背景
- Background: ApoB exists in human plasma in two isoforms, ApoB-48 (Chen et al., 1987) and Apo B-100 (Wei et al., 1985, Yang et al., 1986a, 1989a,b, 1990, Chen et al., 1986, Yang et al., 1990, Yang and Pownall, 1992). Apo B-100 is the major physiological ligand for the LDL receptor. Apo B-100 is a large monomeric protein, containing 4536 amino acids (m.w. 515 kDa, Yang et al., 1986b). Apo B-100 is synthesized in the liver and is required for the assembly of VLDL. It is found in LDL and VLDL after the removal of the Apo A, E and C. Apo B-48 is present in chylomicrons and their remnants. It is essential for the intestinal absorption of dietary lipids. Apo B levels correlate with the risk of coronary disease. The Apo B protein is directly involved in the retention of LDL with the arterial wall (Olofsson and Boren, 2012). Apo B-48 is synthesized in the small intestine. It comprises approximately half of the N-terminal region of ApoB-100 and is the result of posttranscriptional mRNA editing by a stop codon in the intestine not found in the liver.
- 基因ID
- 338
- NCBI登录号
- NP_000375
- UniProt
- P04114
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