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Apo-B100 抗体 (Biotin)

Apo-B100 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal B06 Biotin
产品编号 ABIN7449340
发货至: 中国
  • 抗原 See all Apo-B100 抗体
    Apo-B100 (Apoprotein B100 (Apo-B100))
    适用
    • 6
    • 2
    宿主
    • 5
    • 3
    山羊
    克隆类型
    • 8
    多克隆
    标记
    • 4
    • 2
    • 1
    • 1
    This Apo-B100 antibody is conjugated to Biotin
    应用范围
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    原理
    Goat anti-Human Apo B-100 [B06] Antibody Biotin Conjugated
    免疫原
    Human Apolipoprotein B100
    克隆位点
    B06
    亚型
    IgG
    Top Product
    Discover our top product Apo-B100 Primary Antibody
  • 应用备注

    WB: 1:1,000 - 1:80,000

    ELISA: 1:1,000 - 1:80,000

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    Apo-B100 (Apoprotein B100 (Apo-B100))
    别名
    ApoB-100 (Apo-B100 产品)
    别名
    Ac1-060 antibody, Apo B-100 antibody, ApoB-100 antibody, ApoB-48 antibody, apolipoprotein B antibody, Apob antibody
    背景
    Background: ApoB exists in human plasma in two isoforms, ApoB-48 (Chen et al., 1987) and Apo B-100 (Wei et al., 1985, Yang et al., 1986a, 1989a,b, 1990, Chen et al., 1986, Yang et al., 1990, Yang and Pownall, 1992). Apo B-100 is the major physiological ligand for the LDL receptor. Apo B-100 is a large monomeric protein, containing 4536 amino acids (m.w. 515 kDa, Yang et al., 1986b). Apo B-100 is synthesized in the liver and is required for the assembly of VLDL. It is found in LDL and VLDL after the removal of the Apo A, E and C. Apo B-48 is present in chylomicrons and their remnants. It is essential for the intestinal absorption of dietary lipids. Apo B levels correlate with the risk of coronary disease. The Apo B protein is directly involved in the retention of LDL with the arterial wall (Olofsson and Boren, 2012). Apo B-48 is synthesized in the small intestine. It comprises approximately half of the N-terminal region of ApoB-100 and is the result of posttranscriptional mRNA editing by a stop codon in the intestine not found in the liver.
    基因ID
    338
    NCBI登录号
    NP_000375
    UniProt
    P04114
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