nit2a antibody, 1190017B19Rik antibody, D16Ertd502e antibody, RGD1310494 antibody, zgc:109720 antibody, nitrilase family member 2 S homeolog antibody, nitrilase family member 2 antibody, nitrilase family, member 2 antibody, nit2.S antibody, NIT2 antibody, nit2 antibody, Nit2 antibody
背景
Background: Nitrilase homolog 2 (NIT2) has an omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle [taken from the Universal Protein Resource (UniProt) Q9NQR4].