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KIF20B 抗体 (AA 825-875)

KIF20B 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7449101
发货至: 中国
  • 抗原 See all KIF20B 抗体
    KIF20B (Kinesin Family Member 20B (KIF20B))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 825-875
    适用
    • 12
    • 2
    • 1
    宿主
    • 11
    • 1
    克隆类型
    • 12
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    This KIF20B antibody is un-conjugated
    应用范围
    • 10
    • 8
    • 2
    • 1
    • 1
    • 1
    Immunoprecipitation (IP)
    原理
    Rabbit anti-KIF20B Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    Between AA 825 and 875
    亚型
    IgG
    Top Product
    Discover our top product KIF20B Primary Antibody
  • 应用备注
    8 - 15 μL/mg lysate
    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    KIF20B (Kinesin Family Member 20B (KIF20B))
    别名
    KIF20B (KIF20B 产品)
    别名
    ct90 antibody, mpp1 antibody, krmp1 antibody, mpp-1 antibody, MGC83846 antibody, mphosph1 antibody, KIF20B antibody, MPHOSPH1 antibody, CT90 antibody, KRMP1 antibody, MPP-1 antibody, MPP1 antibody, B130024C23 antibody, C330014J10Rik antibody, Mphosph1 antibody, kinesin family member 20B S homeolog antibody, kinesin family member 20B antibody, kif20b.S antibody, KIF20B antibody, kif20b antibody, Kif20b antibody
    背景
    Background: Kinesin family member 20B (KIF20B) is a plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). KIF20B is required for proper midbody organization and abscission in polarized cortical stem cells. It plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. KIF20B participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, KIF20B cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. It is involved in cerebral cortex growth (By similarity). KIF20B acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). [taken from the Universal Protein Resource (UniProt) Q96Q89].
    基因ID
    9585
    UniProt
    Q96Q89
    途径
    M Phase
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