DRCTNNB1A antibody, HCC antibody, HLD5 antibody, HYCC1 antibody, AB030242 antibody, Drctnnb1a antibody, RGD1562906 antibody, zgc:77228 antibody, fam126a antibody, family with sequence similarity 126 member A antibody, family with sequence similarity 126, member A antibody, family with sequence similarity 126 member A S homeolog antibody, FAM126A antibody, Fam126a antibody, fam126a antibody, fam126a.S antibody
背景
Background: FAM126A is a component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (PubMed:26571211). FAM126A plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P (PubMed:26571211). Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system (PubMed:26571211, PubMed:16951682). FAM126A may also have a role in the beta-catenin/Lef signaling pathway (Probable) [taken from the Universal Protein Resource (UniProt) Q9BYI3].