UIMC1 抗体 (C-Term)
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- 抗原 See all UIMC1 抗体
- UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UIMC1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 原理
- Rabbit anti-RAP80 IHC Antibody, Affinity Purified
- 预测反应
- Gorilla
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 650 and C-term
- 亚型
- IgG
- Top Product
- Discover our top product UIMC1 Primary Antibody
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- 应用备注
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IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
- 限制
- 仅限研究用
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- 浓度
- 250 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))
- 别名
- RAP80 (UIMC1 产品)
- 背景
- Background: RAP80 was first identified as a nuclear protein that interacts with the retinoid-related testis-associated receptor (RTR) and is able to inhibit the interaction of RTR with the N-CoR co-repressor. RAP80 has also been shown to interact with estrogen receptor alpha (ER-alpha) and modulate its activity. The modulation of ER-alpha activity is dependent on the ubiquitin-interacting motif (UIM) of RAP80. The UIM of RAP80 has also been demonstrated to be important for the BRCA1-dependent DNA repair response.
- 基因ID
- 51720
- NCBI登录号
- NP_057374
- UniProt
- Q96RL1
- 途径
- DNA Damage Repair, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus
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