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UBR4 抗体 (AA 5133-5183)

UBR4 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7448995
发货至: 中国
  • 抗原 See all UBR4 抗体
    UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
    抗原表位
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 5133-5183
    适用
    • 23
    • 13
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 18
    • 4
    • 1
    克隆类型
    • 20
    • 3
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBR4 antibody is un-conjugated
    应用范围
    • 12
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    原理
    Rabbit anti-p600 IHC Antibody, Affinity Purified
    预测反应
    Mouse,Rat,Horse,Pig,Orangutan,Monkey,Gorilla,Chimpanzee,Little brown bat,Northern white-cheeked gibbon,White-tufted-ear marmoset
    纯化方法
    Affinity Purified
    免疫原
    Between AA 5133 and 5183
    亚型
    IgG
    Top Product
    Discover our top product UBR4 Primary Antibody
  • 应用备注

    IHC-IF: 1:50 - 1:500

    IHC: 1:100 - 1:500

    限制
    仅限研究用
  • 浓度
    250 μg/mL
    缓冲液
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
    别名
    p600 (UBR4 产品)
    背景
    Background: p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) Q5T4S7].
    基因ID
    23352
    NCBI登录号
    NP_065816
    UniProt
    Q5T4S7
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