UBR4 抗体 (AA 5133-5183)
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- 抗原 See all UBR4 抗体
- UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
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抗原表位
- AA 5133-5183
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBR4 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 原理
- Rabbit anti-p600 IHC Antibody, Affinity Purified
- 预测反应
- Mouse,Rat,Horse,Pig,Orangutan,Monkey,Gorilla,Chimpanzee,Little brown bat,Northern white-cheeked gibbon,White-tufted-ear marmoset
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 5133 and 5183
- 亚型
- IgG
- Top Product
- Discover our top product UBR4 Primary Antibody
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- 应用备注
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IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
- 限制
- 仅限研究用
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- 浓度
- 250 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
- 别名
- p600 (UBR4 产品)
- 别名
- ZUBR1 antibody, RBAF600 antibody, p600 antibody, 1810009A16Rik antibody, A930005E13Rik antibody, D930005K06Rik antibody, Gm1032 antibody, Gm1666 antibody, N28143 antibody, Zubr1 antibody, mKIAA0462 antibody, Rbaf600 antibody, ubiquitin protein ligase E3 component n-recognin 4 antibody, E3 ubiquitin-protein ligase UBR4 antibody, UBR4 antibody, Ubr4 antibody, LOC100511934 antibody
- 背景
- Background: p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) Q5T4S7].
- 基因ID
- 23352
- NCBI登录号
- NP_065816
- UniProt
- Q5T4S7
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