CENPF 抗体 (AA 2350-2400)
-
- 抗原 See all CENPF 抗体
- CENPF (Centromere Protein F (CENPF))
-
抗原表位
- AA 2350-2400
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CENPF antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 原理
- Rabbit anti-CENP-F/Mitosin IHC Antibody, Affinity Purified
- 预测反应
- Orangutan,Gorilla,Chimpanzee
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 2350 and 2400
- 亚型
- IgG
- Top Product
- Discover our top product CENPF Primary Antibody
-
-
- 应用备注
-
IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
- 限制
- 仅限研究用
-
- 浓度
- 100 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
-
- 抗原
- CENPF (Centromere Protein F (CENPF))
- 别名
- CENP-F/Mitosin (CENPF 产品)
- 别名
- LOC100222985 antibody, 6530404A22Rik antibody, AI325968 antibody, CENF antibody, Lek1 antibody, PRO1779 antibody, mitosin antibody, im:7140452 antibody, im:7144238 antibody, im:7154719 antibody, im:7156761 antibody, si:ch211-152h14.2 antibody, hcp-1 antibody, CMF1 antibody, centromere protein F antibody, CENPF antibody, Cenpf antibody, cenpf antibody
- 背景
- Background: Centromere protein F (CENP-F) is a microtubule binding protein and component of the kinetochore. It is essential for kinetochore attachment, chromosome alignment, and the spindle checkpoint. CENP-F appears to be important to the association of the NudE-related proteins Ndel1 and Nde1 to the Lis1/dynein motor complex and their role in kinetochore function. CENP-F is a farnesylated protein and the farnesylation of CENP-F appears to be central to its role in mediating kinetochore-microtubule interactions as well as its degradation after mitosis. Recently, CENP-F expression has been correlated with markers of poor outcome in breast cancer.
- 基因ID
- 1063
- UniProt
- P49454
- 途径
- Chromatin Binding, M Phase, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
-