Rat,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Panda,Orangutan,Monkey,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,Small-eared galago,Thirteen-lined ground squirrel,Chinese hamster,Little brown bat
Background: SMAR1/BANP was identified as a protein that binds the scaffold/matrix associated region of the T-cell receptor beta locus (SMAR1) and as a protein that interacts with BTG3, a member of structurally related proteins that regulate cell proliferation (BANP- BTG-associated nuclear protein). SMAR1/BANP is a DNA binding protein that is reported to be a tumor suppressor and transcriptional repressor. SMAR1/BANP can down-regulate cyclin D1 transcription by binding to the cyclin D1 promoter and through its interaction with HDAC1 (histone deacetylase 1). SMAR1 has also been shown to interact with p53 and modulate its activity.