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BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 175-225) 抗体

BABAM1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7448667
发货至: 中国
  • 抗原 See all BRISC and BRCA1 A Complex Member 1 (BABAM1) 抗体
    BRISC and BRCA1 A Complex Member 1 (BABAM1)
    抗原表位
    • 10
    • 8
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    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 175-225
    适用
    • 26
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 21
    • 4
    • 1
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    非结合性
    应用范围
    • 24
    • 15
    • 13
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    原理
    Rabbit anti-MERIT40 IHC Antibody, Affinity Purified
    预测反应
    Mouse,Rat,Bovine,Dog,Horse,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Small-eared galago,Chinese hamster,Northern white-cheeked gibbon,Crab-eating macaque,Thirteen-lined ground squirrel,Little brown bat
    纯化方法
    Affinity Purified
    免疫原
    Between AA 175 and 225
    亚型
    IgG
    Top Product
    Discover our top product BABAM1 Primary Antibody
  • 应用备注
    1:100 - 1:500
    限制
    仅限研究用
  • 浓度
    250 μg/mL
    缓冲液
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    BRISC and BRCA1 A Complex Member 1 (BABAM1)
    别名
    MERIT40 (BABAM1 产品)
    别名
    merit40 antibody, nba1 antibody, zgc:100909 antibody, c19orf62 antibody, C19orf62 antibody, MERIT40 antibody, NBA1 antibody, C7H19orf62 antibody, 5430437P03Rik antibody, Merit40 antibody, BRISC and BRCA1 A complex member 1 antibody, BRISC and BRCA1 A complex member 1 L homeolog antibody, babam1 antibody, BABAM1 antibody, babam1.L antibody, Babam1 antibody
    背景
    Background: MERIT40 (mediator of RAP80 interactions and targeting subunit of 40 kDa) is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. MERIT40 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin [taken from the Universal Protein Resource (UniProt) Q9NWV8].
    基因ID
    29086
    NCBI登录号
    NP_054892
    UniProt
    Q9NWV8
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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