YTHDF1 抗体
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- 抗原 See all YTHDF1 products
- YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
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适用
- 人, Hamster
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This YTHDF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity Purified
- 克隆位点
- R05-2E7
- 亚型
- IgG
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- 应用备注
- WB 1:1000-1:2000
- 限制
- 仅限研究用
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- 浓度
- 300 μg/mL
- 缓冲液
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
- 别名
- YTHDF1 (YTHDF1 产品)
- 别名
- fb49c02 antibody, zgc:55657 antibody, wu:fb49c02 antibody, wu:fi19h06 antibody, wu:fj87f09 antibody, wu:fp06c11 antibody, MGC75606 antibody, MGC68505 antibody, 2210410K23Rik antibody, 8030473O16 antibody, C20orf21 antibody, YTH N(6)-methyladenosine RNA binding protein 1 antibody, YTH N(6)-methyladenosine RNA binding protein 1 L homeolog antibody, YTH N6-methyladenosine RNA binding protein 1 antibody, YTH domain family 1 antibody, ythdf1 antibody, ythdf1.L antibody, YTHDF1 antibody, Ythdf1 antibody
- 背景
- C20orf21,DF1,YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21, is a 559 amino acid protein, which localizes in the cytoplasm. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation. YTHDF1 exists two isoform and calculated molecular weight of isoforms are 61 kDa and 21 kDa.
- 分子量
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Observed_MW: 61kDa
Calculated_MW: 61kDa
- 基因ID
- 54915
- UniProt
- P59326
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