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RAD50 抗体

RAD50 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7384000
发货至: 中国
  • 抗原 See all RAD50 抗体
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    适用
    • 60
    • 51
    • 17
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 67
    • 4
    克隆类型
    • 65
    • 6
    多克隆
    标记
    • 34
    • 6
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    • 2
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    • 1
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    • 1
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    This RAD50 antibody is un-conjugated
    应用范围
    • 54
    • 17
    • 16
    • 16
    • 13
    • 13
    • 9
    • 9
    • 6
    • 5
    • 3
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    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human RAD50
    亚型
    IgG
    Top Product
    Discover our top product RAD50 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 浓度
    0.4 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    别名
    RAD50 (RAD50 产品)
    背景
    DNA repair protein RAD50,hRAD50,hsRAD50,Mrell,NBSLD,Rad 50,RAD50 2,rad50,RAD50 homolog (S cerevisiae),RAD50 homolog,RAD50 PEN,RAD50,S. cerevisiae,homolog of,RAD50,RAD502,Rad50l,Truncated RAD50 protein,The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
    分子量
    154 kDa
    NCBI登录号
    NP_005723
    UniProt
    Q92878
    途径
    DNA Damage Repair, Protein targeting to Nucleus
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