HUP48,OTTHUMP00000030407,Paired box 1,Paired box gene 1,Paired box protein Pax 1,Paired box protein Pax-1,Paired domain gene HuP48,PAX 1,Pax1,PAX1,This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations