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SARS-CoV-2 Spike S2 抗体

适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: Human, 小鼠 Monoclonal D001 unconjugated
产品编号 ABIN7383760
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike S2 抗体
    SARS-CoV-2 Spike S2
    适用
    SARS Coronavirus-2 (SARS-CoV-2)
    宿主
    • 6
    • 3
    • 1
    Human, 小鼠
    克隆类型
    • 5
    • 5
    单克隆
    标记
    • 8
    • 2
    This SARS-CoV-2 Spike S2 antibody is un-conjugated
    应用范围
    • 8
    • 3
    • 2
    • 1
    • 1
    ELISA
    特异性
    SARS-COV-2 Spike S2 Monoclonal Antibody(2019-nCoV)
    纯化方法
    Antigen affinity purification
    免疫原
    Recombinant 2019-nCoV S2 Protein (ECD, His Tag),PKSR030505
    克隆位点
    D001
    亚型
    IgG1
    Top Product
    Discover our top product SARS-CoV-2 Spike S2 Primary Antibody
  • 应用备注
    ELISA: 1:5,000-1:10,000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    0.2 μm filtered solution in PBS
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SARS-CoV-2 Spike S2
    Abstract
    SARS-CoV-2 Spike S2 产品
    别名
    E2 antibody, Surface Glycoprotein antibody, S antibody
    物质类
    Viral Protein
    背景
    Coronavirus s2,coronavirus spike,cov spike,ncov,ncov s2,ncov spike,novel coronavirus s2,novel coronavirus spike,s2,Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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