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Recombinant SARS-CoV-2 Spike 抗体 (RBD)

MALS verified 适用: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta, SARS CoV-2 Gamma 宿主: 小鼠 Monoclonal AM334 unconjugated Recombinant Antibody
产品编号 ABIN7271751
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike 抗体
    SARS-CoV-2 Spike
    抗体类型
    Recombinant Antibody
    抗原表位
    • 38
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    RBD
    适用
    • 63
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta, SARS CoV-2 Gamma
    宿主
    • 25
    • 24
    • 14
    • 2
    • 2
    • 1
    小鼠
    克隆类型
    • 42
    • 12
    • 11
    单克隆
    标记
    • 56
    • 5
    • 3
    • 1
    This SARS-CoV-2 Spike antibody is un-conjugated
    应用范围
    请咨询
    原理
    Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (AM334) (Beta & Gamma Specific) (MALS verified)
    特异性
    This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. No cross-reactivity is detected with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.
    产品特性
    Recombinant Antibodies produced in HEK293. Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Beta & Gamma Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Beta (B.1.351) and Gamma (P.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus, the Alpha (B.1.1.7) variant, the Delta (B.1.617.2) variant and the Omicron (B.1.1.529, BA.2) variant.
    质量等级
    MALS verified
    免疫原
    Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Beta & Gamma Specific) (ABIN7271751 and ABIN7273339) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Beta (B.1.351) and Gamma (P.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus, the Alpha (B.1.1.7) variant, the Delta (B.1.617.2) variant and the Omicron (B.1.1.529, BA.2) variant.
    克隆位点
    AM334
    亚型
    IgG1
    Top Product
    Discover our top product SARS-CoV-2 Spike Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    -80 °C
    储存方法
    -70°C
  • 抗原
    SARS-CoV-2 Spike
    Abstract
    SARS-CoV-2 Spike 产品
    别名
    E2 antibody, E2 glycoprotein precursor antibody, Surface Glycoprotein antibody, S antibody
    背景
    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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