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WT1 抗体

WT1 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7271368
发货至: 中国
  • 抗原 See all WT1 抗体
    WT1 (Wilms Tumor 1 (WT1))
    适用
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    宿主
    • 81
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    克隆类型
    • 87
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    单克隆
    标记
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    This WT1 antibody is un-conjugated
    应用范围
    • 89
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    Immunohistochemistry (IHC), Western Blotting (WB)
    原理
    WT1 Rabbit mAb
    交叉反应
    小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human WT1.
    亚型
    IgG
    Top Product
    Discover our top product WT1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    WT1 (Wilms Tumor 1 (WT1))
    别名
    Wilms Tumor Protein (WT1 产品)
    背景
    This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.,WT1, AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33, Wilms tumor 1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor biomarkers,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Wilms Tumor Protein
    分子量
    55kDa
    基因ID
    7490
    UniProt
    P19544
    途径
    Tube Formation
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