scar1 antibody, wave1 antibody, ATRANGAP2 antibody, ATSCAR1 antibody, SCAR1 antibody, T14G11.27 antibody, T14G11_27 antibody, WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 1 antibody, wave antibody, WAVE antibody, WAVE1 antibody, AI195380 antibody, AI838537 antibody, Scar antibody, WAVE-1 antibody, WAS protein family member 1 S homeolog antibody, SCAR family protein antibody, WAS protein family member 1 antibody, WAS protein family, member 1 antibody, wasf1.S antibody, AT2G34150 antibody, wasf1 antibody, WASF1 antibody, Wasf1 antibody
背景
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.,WASF1,SCAR1,WAVE,WAVE1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Extracellular Matrix,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,WASF1