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- 抗原 See all UPF3A 抗体
- UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
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抗原表位
- AA 327-476
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UPF3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 原理
- UPF3A Rabbit pAb
- 序列
- EGSLEEPQET SHSGSDKEHR DVERSQEQES EAQRYHVDDG RRHRAHHEPE RLSRRSEDEQ RWGKGPGQDR GKKGSQDSGA PGEAMERLGR AQRCDDSPAP RKERLANKDR PALQLYDPGA RFRARECGGN RRICKAEGSG TGPEKREEAE
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 327-476 of human UPF3A (NP_075387.1).
- 亚型
- IgG
- Top Product
- Discover our top product UPF3A Primary Antibody
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anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 274-374) antibody
UPF3A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 1-443) antibodyUPF3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 382-475) antibodyUPF3A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 359-408) antibodyUPF3A 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
- 别名
- UPF3A (UPF3A 产品)
- 别名
- 2600001C03Rik antibody, 4930546M19Rik antibody, RENT3A antibody, UPF3 antibody, UPF3A antibody, HUPF3A antibody, si:dkey-21o13.6 antibody, UPF3 regulator of nonsense transcripts homolog A (yeast) antibody, UPF3A, regulator of nonsense mediated mRNA decay antibody, Upf3a antibody, UPF3A antibody, upf3a antibody
- 背景
- This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Two splice variants encoding different isoforms have been found for this gene.,UPF3A,HUPF3A,RENT3A,UPF3,Epigenetics & Nuclear Signaling,Signal Transduction,UPF3A
- 分子量
- 17kDa/51kDa/54kDa
- 基因ID
- 65110
- UniProt
- Q9H1J1
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