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ULK3 抗体

This anti-ULK3 antibody is a 兔 单克隆 antibody detecting ULK3 in WB 和 IF. Suitable for 人.
产品编号 ABIN7271222
发货至: 中国

Quick Overview for ULK3 抗体 (ABIN7271222)

抗原

See all ULK3 抗体
ULK3 (Unc-51-Like Kinase 3 (ULK3))

适用

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宿主

  • 47
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克隆类型

  • 50
  • 6
单克隆

标记

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This ULK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 原理

    ULK3 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human ULK3

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ULK3 (Unc-51-Like Kinase 3 (ULK3))

    别名

    ULK3

    背景

    Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3. Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.,Autophagy,Cell Biology & Developmental Biology,Endocrine & Metabolism,Kinase,Mitochondrial metabolism,Signal Transduction,ULK3

    分子量

    53kDa

    基因ID

    25989

    UniProt

    Q6PHR2
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