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ULK3 抗体

ULK3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7271222
发货至: 中国
  • 抗原 See all ULK3 抗体
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    适用
    • 53
    • 46
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 61
    • 6
    • 2
    克隆类型
    • 65
    • 4
    单克隆
    标记
    • 30
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ULK3 antibody is un-conjugated
    应用范围
    • 60
    • 40
    • 10
    • 9
    • 8
    • 6
    • 3
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    ULK3 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human ULK3
    亚型
    IgG
    Top Product
    Discover our top product ULK3 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    别名
    ULK3 (ULK3 产品)
    别名
    zgc:162196 antibody, 1200015E14Rik antibody, unc-51 like kinase 3 antibody, unc-51 like kinase 3 L homeolog antibody, unc-51-like kinase 3 antibody, ULK3 antibody, ulk3 antibody, Ulk3 antibody, ulk3.L antibody
    背景
    Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3. Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.,Autophagy,Cell Biology & Developmental Biology,Endocrine & Metabolism,Kinase,Mitochondrial metabolism,Signal Transduction,ULK3
    分子量
    53kDa
    基因ID
    25989
    UniProt
    Q6PHR2
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