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USP37 抗体 (AA 150-250)

This anti-USP37 antibody is a 兔 多克隆 antibody detecting USP37 in WB. Suitable for 人.
产品编号 ABIN7271158
发货至: 中国

Quick Overview for USP37 抗体 (AA 150-250) (ABIN7271158)

抗原

See all USP37 抗体
USP37 (Ubiquitin Specific Peptidase 37 (USP37))

适用

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宿主

  • 31

克隆类型

  • 31
多克隆

标记

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This USP37 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 150-250

    原理

    USP37 Rabbit pAb

    序列

    SLETKDDIPF RKVLGNPGRG SIKTVAGSGI ARTIPSLTST STPLRSGLLE NRTEKRKRMI STGSELNEDY PKENDSSSNN KAMTDPSRKY LTSSREKQLS L

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 150-250 of human USP37 (NP_065986.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    USP37 (Ubiquitin Specific Peptidase 37 (USP37))

    别名

    USP37

    背景

    Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2, thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2. Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1.,USP37,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,USP37

    分子量

    99kDa/110kDa

    基因ID

    57695

    UniProt

    Q86T82
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