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TYROBP 抗体 (C-Term)

TYROBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7271115
发货至: 中国
  • 抗原 See all TYROBP 抗体
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    抗原表位
    • 16
    • 15
    • 13
    • 8
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 51
    • 20
    • 4
    宿主
    • 68
    • 1
    • 1
    克隆类型
    • 61
    • 9
    多克隆
    标记
    • 19
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    • 3
    • 3
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    • 2
    • 2
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    • 2
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    This TYROBP antibody is un-conjugated
    应用范围
    • 38
    • 30
    • 26
    • 26
    • 18
    • 15
    • 12
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    TYROBP Rabbit pAb
    序列
    DLVLTVLIAL AVYFLGRLVP RGRGAAEAAT RKQRITETES PYQELQGQRS DVYSDLNTQR PYYK
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TYROBP (NP_003323.1).
    亚型
    IgG
    Top Product
    Discover our top product TYROBP Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    别名
    TYROBP (TYROBP 产品)
    背景
    This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.,TYROBP,DAP12,KARAP,PLOSL,Signal Transduction,TYROBP
    分子量
    11kDa/12kDa
    基因ID
    7305
    UniProt
    O43914
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