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TYROBP 抗体 (C-Term)

TYROBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7271115
发货至: 中国
  • 抗原 See all TYROBP 抗体
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    抗原表位
    • 16
    • 15
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    C-Term
    适用
    • 52
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    宿主
    • 69
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    克隆类型
    • 62
    • 9
    多克隆
    标记
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    This TYROBP antibody is un-conjugated
    应用范围
    • 40
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    Western Blotting (WB)
    原理
    TYROBP Rabbit pAb
    序列
    DLVLTVLIAL AVYFLGRLVP RGRGAAEAAT RKQRITETES PYQELQGQRS DVYSDLNTQR PYYK
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TYROBP (NP_003323.1).
    亚型
    IgG
    Top Product
    Discover our top product TYROBP Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    别名
    TYROBP (TYROBP 产品)
    别名
    TYROBP antibody, DAP12 antibody, tyrpbp antibody, Karap antibody, KARAP antibody, PLOSL antibody, Ly83 antibody, dap12 antibody, TYRO protein tyrosine kinase binding protein antibody, Tyro protein tyrosine kinase binding protein antibody, TYROBP antibody, tyrobp antibody, Tyrobp antibody
    背景
    This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.,TYROBP,DAP12,KARAP,PLOSL,Signal Transduction,TYROBP
    分子量
    11kDa/12kDa
    基因ID
    7305
    UniProt
    O43914
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