fi42c05 antibody, im:7140344 antibody, wu:fi42c05 antibody, zgc:152898 antibody, MGC115225 antibody, SHEP10 antibody, TPC2 antibody, BC025890 antibody, D830047E22Rik antibody, two pore segment channel 2 antibody, two pore segment channel 2 L homeolog antibody, two pore calcium channel protein 2 antibody, tpcn2 antibody, Tpcn2 antibody, TPCN2 antibody, tpcn2.L antibody, LOC100444397 antibody
背景
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.,TPCN2,SHEP10,TPC2,Signal Transduction,Neuroscience,Calcium Signaling,TPCN2