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TNFSF9 抗体

TNFSF9 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7271060
发货至: 中国
  • 抗原 See all TNFSF9 抗体
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    适用
    • 66
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    宿主
    • 49
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    克隆类型
    • 47
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    单克隆
    标记
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    This TNFSF9 antibody is un-conjugated
    应用范围
    • 48
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    Western Blotting (WB)
    原理
    4-1BBL/CD137L Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human 4-1BBL/CD137L
    亚型
    IgG
    Top Product
    Discover our top product TNFSF9 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    别名
    TNFSF9 (TNFSF9 产品)
    别名
    TNFSF9 antibody, 4-1BB-L antibody, 4-1BBL antibody, AI848817 antibody, Cd137l antibody, Ly63l antibody, CD137L antibody, TNF superfamily member 9 antibody, tumor necrosis factor (ligand) superfamily, member 9 antibody, Tnfsf9 antibody, LOC476729 antibody, TNFSF9 antibody
    背景
    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008],4-1BB-L, CD137L, TNLG5A,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,Cytokines_TNF,Growth factors,Growth factors_TNF,Immunology & Inflammation,TNFSF9
    分子量
    25-32kDa
    基因ID
    8744
    UniProt
    P41273
    途径
    Activated T Cell Proliferation, Cancer Immune Checkpoints
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