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TPSB2 抗体

TPSB2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7271017
发货至: 中国
  • 抗原 See all TPSB2 抗体
    TPSB2 (Tryptase beta 2 (TPSB2))
    适用
    • 21
    • 18
    • 17
    宿主
    • 43
    • 1
    • 1
    • 1
    克隆类型
    • 44
    • 2
    单克隆
    标记
    • 14
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TPSB2 antibody is un-conjugated
    应用范围
    • 22
    • 21
    • 9
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Mast Cell Tryptase (TPSB2) Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Mast Cell Tryptase (TPSB2) (TPSB2)
    亚型
    IgG
    Top Product
    Discover our top product TPSB2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TPSB2 (Tryptase beta 2 (TPSB2))
    别名
    TPSB2 (TPSB2 产品)
    别名
    TPS2 antibody, tryptaseB antibody, tryptaseC antibody, Mcpt6 antibody, tryptase beta 2 (gene/pseudogene) antibody, tryptase beta 2 antibody, TPSB2 antibody, Tpsb2 antibody
    背景
    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008],TPS2, tryptaseB, tryptaseC,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Immunology & Inflammation,Ubiquitin,TPSB2
    分子量
    30kDa
    基因ID
    64499
    UniProt
    P20231
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