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TIRAP 抗体

TIRAP 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7270842
发货至: 中国
  • 抗原 See all TIRAP 抗体
    TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
    适用
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    宿主
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    克隆类型
    • 64
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    单克隆
    标记
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    This TIRAP antibody is un-conjugated
    应用范围
    • 32
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    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    TIRAP Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human TIRAP
    亚型
    IgG
    Top Product
    Discover our top product TIRAP Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
    别名
    TIRAP (TIRAP 产品)
    别名
    mal antibody, wyatt antibody, BACTS1 antibody, Mal antibody, MyD88-2 antibody, AA407980 antibody, C130027E04Rik antibody, Tlr4ap antibody, Wyatt antibody, toll-interleukin 1 receptor (TIR) domain containing adaptor protein antibody, TIR domain containing adaptor protein antibody, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog antibody, toll-interleukin 1 receptor (TIR) domain-containing adaptor protein antibody, tirap antibody, TIRAP antibody, tirap.L antibody, Tirap antibody
    背景
    The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described. [provided by RefSeq, Jul 2008],BACTS1, Mal, MyD88-2, wyatt,Cardiovascular,Cell Intrinsic Innate Immunity Signaling Pathway,Immunology & Inflammation,Innate Immunity_TLR Signaling,Kinase,Toll-like Receptor Signaling Pathway,TIRAP
    分子量
    28kDa
    基因ID
    114609
    UniProt
    P58753
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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