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TPMT 抗体

TPMT 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7270797
发货至: 中国
  • 抗原 See all TPMT 抗体
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    适用
    • 41
    • 12
    • 11
    • 2
    • 2
    宿主
    • 32
    • 9
    克隆类型
    • 31
    • 10
    单克隆
    标记
    • 24
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TPMT antibody is un-conjugated
    应用范围
    • 29
    • 19
    • 16
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    TPMT Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of Human TPMT.
    亚型
    IgG
    Top Product
    Discover our top product TPMT Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    别名
    TPMT (TPMT 产品)
    背景
    This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.,TPMT,TPMTD,Signal Transduction,Endocrine & Metabolism,Drug metabolism,TPMT
    分子量
    28kDa
    基因ID
    7172
    UniProt
    P51580
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