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- 抗原 See all TNKS2 抗体
- TNKS2 (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))
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抗原表位
- AA 780-1050
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNKS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- TNKS2 Rabbit pAb
- 序列
- TPLDLVSADD VSALLTAAMP PSALPSCYKP QVLNGVRSPG ATADALSSGP SSPSSLSAAS SLDNLSGSFS ELSSVVSSSG TEGASSLEKK EVPGVDFSIT QFVRNLGLEH LMDIFEREQI TLDVLVEMGH KELKEIGINA YGHRHKLIKG VERLISGQQG LNPYLTLNTS GSGTILIDLS PDDKEFQSVE EEMQSTVREH RDGGHAGGIF NRYNILKIQK VCNKKLWERY THRRKEVSEE NHNHANERML FHGSPFVNAI IHKGFDERHA Y
- 交叉反应
- 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 780-1050 of human TNKS2 (NP_079511.1).
- 亚型
- IgG
- Top Product
- Discover our top product TNKS2 Primary Antibody
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anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (AA 1-246) antibody
TNKS2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) antibodyTNKS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (N-Term) antibodyTNKS2 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (Internal Region) antibodyVerified TNKS2 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (Internal Region) antibodyVerified TNKS2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (AA 959-1166) antibodyTNKS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (AA 1126-1156), (C-Term) antibodyTNKS2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB14166 unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- TNKS2 (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))
- 别名
- TNKS2 (TNKS2 产品)
- 别名
- ARTD6 antibody, PARP-5b antibody, PARP-5c antibody, PARP5B antibody, PARP5C antibody, TANK2 antibody, TNKL antibody, pART6 antibody, 5430432P15Rik antibody, AA517131 antibody, AI662480 antibody, TNKS-2 antibody, Tank2 antibody, tankyrase-2 antibody, TNKS2 antibody, tankyrase-1 antibody, tnks antibody, tnks.L antibody, tnks2 antibody, tankyrase 2 antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 antibody, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase S homeolog antibody, TNKS2 antibody, Tnks2 antibody, tnks2 antibody, tnks.S antibody
- 背景
- Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. Stimulates 26S proteasome activity.,TNKS2,ARTD6,PARP-5b,PARP-5c,PARP5B,PARP5C,TANK2,TNKL,pART6,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Wnt/β-Catenin Signaling Pathway,TNKS2
- 分子量
- 126kDa
- 基因ID
- 80351
- UniProt
- Q9H2K2
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