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SOCS2 抗体

SOCS2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7270641
发货至: 中国
  • 抗原 See all SOCS2 抗体
    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
    适用
    • 40
    • 17
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 40
    • 3
    克隆类型
    • 33
    • 10
    单克隆
    标记
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This SOCS2 antibody is un-conjugated
    应用范围
    • 17
    • 12
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    SOCS2 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human SOCS2
    亚型
    IgG
    Top Product
    Discover our top product SOCS2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
    别名
    SOCS2 (SOCS2 产品)
    别名
    CIS2 antibody, Cish2 antibody, SOCS-2 antibody, SSI-2 antibody, SSI2 antibody, STATI2 antibody, Cish1 antibody, Socs-1 antibody, Socs-2 antibody, si:dkey-202b22.1 antibody, socs2 antibody, cis2 antibody, ssi2 antibody, cish2 antibody, ssi-2 antibody, socs-2 antibody, stati2 antibody, 8030460M17 antibody, AI527257 antibody, AW108012 antibody, D130043N08Rik antibody, JAB antibody, hg antibody, Cradd antibody, Socs2 antibody, suppressor of cytokine signaling 2 antibody, suppressor of cytokine signaling 1 antibody, death domain-containing protein CRADD antibody, suppressor of cytokine signaling 2 S homeolog antibody, SOCS2 antibody, Socs1 antibody, Socs2 antibody, socs2 antibody, LOC100716104 antibody, socs2.S antibody
    背景
    This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2,Apoptosis,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Neuroscience,Signal Transduction,SOCS2
    分子量
    22kDa
    基因ID
    8835
    UniProt
    O14508
    途径
    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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