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- 抗原 See all SPRY3 抗体
- SPRY3 (Sprouty Homolog 3 (SPRY3))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPRY3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- SPRY3 Rabbit pAb
- 序列
- TDDEDNCADE PCSCGPSSCF VRWAAMSLIS LFLPCLCCYL PTRGCLHLCQ QGYDSLRRPG CRCKRHTNTV CRKISSGSAP FPKAQEKSV
- 交叉反应
- 人
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human SPRY3 (NP_005831.1).
- 亚型
- IgG
- Top Product
- Discover our top product SPRY3 Primary Antibody
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anti-Sprouty Homolog 3 (SPRY3) (AA 91-288) antibody
SPRY3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 261-288), (C-Term) antibodySPRY3 适用: 人 WB 宿主: 兔 Polyclonal RB32263 unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 71-120) antibodySPRY3 适用: 人, 小鼠, 兔, Cow, 豚鼠, 马, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 38-87) antibodySPRY3 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 91-288) antibodySPRY3 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sprouty Homolog 3 (SPRY3) (AA 88-281) antibodySPRY3 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SPRY3 (Sprouty Homolog 3 (SPRY3))
- 别名
- SPRY3 (SPRY3 产品)
- 别名
- HSPRY3 antibody, spry-3 antibody, Gm1409 antibody, Gm391 antibody, sprouty3 antibody, RGD1562172 antibody, sprouty RTK signaling antagonist 3 antibody, sprouty homolog 3 (Drosophila) antibody, SPRY3 antibody, Spry3 antibody
- 背景
- Members of the Sprouty family (Sprouty 1-4) are inducible negative regulators of growth factors that act through tyrosine kinase receptors. Mammalian Sprouty homologs share a well-conserved cysteine-rich carboxy-terminal domain with their Drosophila counterparts. Sprouty proteins are cytoplasmic in unstimulated cells, but in cells stimulated by growth factors they anchor to the plasma membrane by palmitoylation. Sprouty 1 and 2 associate with caveolin-1 in perinuclear and vesicular structures and are phosphorylated on serine residues. Sprouty 2 can associate with c-Cbl, a downregulator of RTK signaling, and inhibit the activities of several growth factors. Unlike the widely expressed Sprouty members 1, 2 and 4, Sprouty 3 expression is restricted to adult brain and testis. Sprouty 4 is a target of the WNT/b-catenin signaling pathway in progenitor cells. In conclusion, members of Sprouty inhibit FGF and VEGF-mediated cell proliferation, suggesting that they may regulate angiogenesis in normal and disease processes.,SPRY3,spry-3,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,SPRY3
- 分子量
- 31kDa
- 基因ID
- 10251
- UniProt
- O43610
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