SGPL1 抗体 (AA 60-390)
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北京 101111
Quick Overview for SGPL1 抗体 (AA 60-390) (ABIN7270533)
抗原
See all SGPL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-390
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原理
- SGPL1 Rabbit pAb
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序列
- VFQPESLWSR FKKKCFKLTR KMPIIGRKIQ DKLNKTKDDI SKNMSFLKVD KEYVKALPSQ GLSSSAVLEK LKEYSSMDAF WQEGRASGTV YSGEEKLTEL LVKAYGDFAW SNPLHPDIFP GLRKIEAEIV RIACSLFNGG PDSCGCVTSG GTESILMACK AYRDLAFEKG IKTPEIVAPQ SAHAAFNKAA SYFGMKIVRV PLTKMMEVDV RAMRRAISRN TAMLVCSTPQ FPHGVIDPVP EVAKLAVKYK IPLHVDACLG GFLIVFMEKA GYPLEHPFDF RVKGVTSISA DTHKYGYAPK GSSLVLYSDK KYRNYQFFVD TDWQGGIYAS P
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 60-390 of human SGPL1 (NP_003892.2).
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亚型
- IgG
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anti-Sphingosine-1-Phosphate Lyase 1 (SGPL1) (AA 239-493) antibody
SGPL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Lyase 1 (SGPL1) antibodySGPL1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Lyase 1 (SGPL1) (AA 301-400) antibodySGPL1 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Lyase 1 (SGPL1) (AA 382-568) antibodySGPL1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Lyase 1 (SGPL1) (AA 72-101) antibodySGPL1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Lyase 1 (SGPL1) (AA 1-568) antibodySGPL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Lyase 1 (SGPL1) (AA 459-568) antibodySGPL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Lyase 1 (SGPL1) (AA 1-568) antibodySGPL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Lyase 1 (SGPL1) (AA 72-101), (N-Term) antibodySGPL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32402 unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))
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别名
- SGPL1
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背景
- Cleaves phosphorylated sphingoid bases (PSBs, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro-inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP (By similarity. Seems to play a role in establishing neuronal contact sites and axonal maintenance (By similarity.,SGPL1,S1PL,SPL,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,SGPL1
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分子量
- 63kDa
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基因ID
- 8879
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UniProt
- O95470
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途径
- Platelet-derived growth Factor Receptor Signaling
抗原
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